—Sir would you mind my sitting next to you?—. My father will sit here in a minute.A. Neve

问题补充：

—Sir, would you mind my sitting next to you?

—. My father will sit here in a minute.

A. Never mind

B. Not at all

C. Of course not

D. You’d better not

答案：

A. Never mind

B. Not at all

C. Of course not

(答案→)D. You’d better not

解析：Never mind 没有关系，不要放在心上；Not at all一点也不；Of course not当然不了；You’d better not你最好别。句意：先生，你介意我坐在你旁边吗？根据下文，一分钟后我父亲要坐在这儿。可知前文表示否定含义，选D最符合语境。