蒽环类耐药,anthracycline-resistant
1)anthracycline-resistant蒽环类耐药
1.Paclitaxel and cisplatin in treatment ofanthracycline-resistant advanced breast carcinoma;紫杉醇联合顺铂治疗30例蒽环类耐药性晚期乳腺癌的疗效分析
2.Objective To evaluate the efficacy and toxicity of vinorelbine(NVB) plus cisplatin(DDP) in the treatment ofanthracycline-resistant advanced breast cancer.目的观察长春瑞滨(vinorelbine,NVB)联合顺铂(cisplatin,DDP)组成的NP方案治疗蒽环类耐药晚期乳腺癌患者的疗效和毒副反应。
英文短句/例句
1.The Present Treatment and Thinking of Anthracycline-resistant Metastatic Breast Cancer蒽环类耐药转移性乳腺癌的治疗现状与思考
2.Clinical Observation on Gemcitabine Combined with Capecitabine in the Treatment of Anthracyclines-Resistant Breast Cancer吉西他滨联合卡培他滨治疗蒽环类耐药的晚期乳腺癌的临床观察
3.Docetaxel and Xeloda Combined Chemotherapy in Anthracyclines Resistant Advanced Breast Cancer多西他赛联合希罗达治疗蒽环类耐药性晚期乳腺癌
4.Paclitexal-based combination chemotherapy in the treatment of fourty-six patients with anthracycline-resistant advanced breast cancer紫杉醇为主的联合方案治疗蒽环类耐药的晚期乳腺癌46例
bination of Gemcitabine and Vinorelbine in the Treatment for 24 Cases of Advanced Breast Cancer with Taxanes/Anthracyclines Resistance吉西他滨联合长春瑞滨治疗蒽环类/紫杉类耐药晚期乳腺癌24例
6.Mitomycin Combined with Cisplatin in the Treatment of 23 Cases with Anthracycline and Taxane-Resistant Advanced Breast Cancer丝裂霉素联合顺铂治疗蒽环类及紫杉类耐药晚期乳腺癌23例
7.An analysis on clinical efficacy of vinorelbine combined with gemcitabine for patients with anthracycline-and taxane-refractory metastatic breast cancer长春瑞滨联合吉西他滨治疗蒽环类和紫杉类药物耐药的转移性乳腺癌的临床疗效分析
8.Experimental and Clinical Study on Drug-resistant Mechanisms and Management Strategies of Myeloid Leukemia Cells Induced by Anthracyclines;蒽环类抗肿瘤药物致髓系白血病细胞耐药机制及应对策略的基础和临床研究
9.Efficacy and Toxicity of Gemcitabine in Combination with Vinorelbine on Metastatic Breast Cancer;吉西他滨联合长春瑞滨治疗蒽环类和紫杉类耐药的转移性乳腺癌的疗效和安全性评价
10.Clinical Comparison of Gemcitabine Combined Cisplatin Regimen Versus Vinorelbine Combined Cisplatin Regimen as Chemotherapy for Anthracycline-and Taxane-resistant Metastatic Breast CancerGP与NP方案治疗对蒽环类及紫杉类均耐药的转移性乳腺癌的疗效观察
11.Gemcitabine and cisplatin combination chemotherapy as alternative agents for metastatic breast cancer patients with anthracycline and taxane resistance吉西他滨联合顺铂治疗蒽环类及紫杉类耐药转移性乳腺癌的临床观察
12.Treatment of anthracycline extravasation with dexrazoxane右丙亚胺成功治疗蒽环类药物外渗的临床研究
13.The effect of creatine phosphate on myocardial injure induced by marcellomycin磷酸肌酸治疗蒽环类药物心肌损害的效果比较
14.Resonance Rayleigh Scattering Spectra Method for the Determination of Anthracycline Anticancer Drugs with CdS Nanoparticles as Probe硫化镉纳米微粒作探针共振瑞利散射测定某些蒽环类抗癌药物
15.Clinical Study of Cardiac Function in Malignant Patients Treated with Anthracycline Using Tissue Doppler Imaging;组织多普勒检测蒽环类药物对肿瘤患者心脏功能的影响
16.Clinical Study of Echocardiography in Assessment of Cardiotoxity in Breast Cancer Patients Treated with Anthracycline;超声心动图评价蒽环类药对乳腺癌患者心脏毒性的临床研究
17.Clinical Study of Myocardial Integrated Backscatter Parameters in Assessment of Cardiotoxity of Patients Treated with Anthracycline;心肌背向散射积分参数评价蒽环类抗肿瘤药心脏毒性的临床研究
18.Predictive Value of FHL1 in Breast Cancer Neoadjuvant Docetaxel and Anthracycline ChemotherapyFHL1在乳腺癌紫杉联合蒽环类药物新辅助化疗中的预测价值
相关短句/例句
Antracycline蒽环类药
parative Study of the Combined Chemotherapy with Paclitaxel orAntracycline for Advanced Breast Cancer紫杉醇及蒽环类药物联合化疗治疗晚期乳腺癌的临床观察
3)Anthracycline蒽环类药物
1.In vitro study onAnthracycline-induced injury of cardiomyocyte H9c2;蒽环类药物心肌损害的体外实验
2.Recent advances of reactive oxygen species and cytotoxicity of anthracycline on leukemia cells;蒽环类药物对白血病细胞的细胞毒作用与活性氧的关系研究进展
3.Clinical Study of Shenmai injection treatment for patients with cardio-toxicity caused by anthracycline;参麦注射液治疗蒽环类药物所致心脏毒性的临床研究
4)marcellomycin蒽环类药物
1.Objective To observe the heart protection effect of parenteral solution Shenqifuzheng in the chemotherapy withmarcellomycin.目的:观察参芪扶正液抗蒽环类药物化疗所致心脏毒性的作用。
5)anthracycline-resistant metastatic breast cancer蒽环类耐药转移性乳腺癌
1.Clinical oncologists should deliver chemotherapy based on evidence-based medicine and standardization for patients withanthracycline-resistant metastatic breast cancer,pay attention to individual treatment,and only this can make a new breakthrough in the treatment of patients with this disease.肿瘤学工作者应以循证医学为指导,合理选择化疗方案,注重个体化治疗,才能在蒽环类耐药转移性乳腺癌的治疗上取得新突破。
6)anthracycline anticancer drug蒽环类抗癌药物
1.5 weakly acidic medium, congo red can react with ananthracycline anticancer drug such as epirubicin, daunorubicin or mitoxantrone.文中研究了反应产物的吸收、荧光和RRS光谱特征,适宜的反应条件及分析化学性质,据此发展了一种用RRS技术灵敏、简便、快速测定蒽环类抗癌药物的新方法。
2.In a neutral or weak alkaline medium,the gold nanoparticle can combine with ananthracycline anticancer drugs such as epirubicin,daunorubicin or mitoxantrone by the virtue of electrostatic and hydro-phobic interaction,forming aggregate with bigger diameters.在近中性至弱碱性介质中,金纳米微粒与表柔比星(EPI)、柔红霉素(DNR)和米托蒽醌(MXT)等蒽环类抗癌药物借静电引力、疏水作用力结合,形成粒径更大的聚集体,导致共振瑞利散射(RRS)的显著增强并产生新的RRS光谱,三种结合产物的最大RRS峰均位于313nm附近,并在510～610nm之间有一宽的散射带。
3.The distribution and relative dose of theanthracycline anticancer drug Doxorubicin in the cell are reflected by its autofluorescence.利用蒽环类抗癌药物阿霉素的自发荧光可反映药物在细胞中的分布和相对剂量；利用特异性荧光探针Hoechst33342(Ho。
延伸阅读
蒽环类抗生素分子式：CAS号：性质：又称蒽环糖苷类抗生素(anthracycline glycoside antibiotics)。基本骨架为7,8,9,10-四氢-5,12-并四苯简称为蒽环酮(an-thracyclinone)的苷元结构，蒽环酮与各种糖以及糖与糖之间苷键连接的不同，组成了结构不同的蒽环类抗生素。多为脂溶性化合物，天然生物发酵过程中产生菌多为放线菌，发酵活性产物在菌丝体内含量为主，经处理后可用有机溶剂提取，进而分离纯化后得到橙红色或黄色晶形粉末。其盐酸盐溶于水和低级醇。分子中的蒽醌为发色团部分，在酸中为红色，碱中呈蓝紫色，常具有指示剂性质，并具有光学活性，水解后可得到蒽环酮和糖的部分。特征紫外吸收峰为235～237nm，255～260nm，290～295nm(甲醇)，在450～590nm左右有强而宽的可见光吸收峰。有一定的抗细菌作用，主要有较强的抗肿瘤活性，但多数具有程度不同的毒副作用。到目前为止该类抗生素在临床上有显著抗肿瘤疗效的日渐增多。主要代表有正定霉素(zhengdingmeisu)、阿霉素(adriamycin)、洋红霉素(carminomycin)和阿克拉霉素(aclacinomycin)等。
