未折叠蛋白反应,Unfolded protein response
1)Unfolded protein response未折叠蛋白反应
1.The Study on Cholesterol Induced Unfolded Protein Response and Acyl-CoA Cholesterol Acyltransferase-2 Expression;胆固醇诱导未折叠蛋白反应及其调节酰基辅酶A胆固醇酰基转移酶2基因的表达
2.The unfolded protein response: its roles in physiological function and disease;未折叠蛋白反应及其在生理功能与疾病中的作用
3.Unfolded protein response involves in acute renal ischemia/reperfusion injury in mice未折叠蛋白反应参与小鼠急性肾缺血/再灌注损伤
英文短句/例句
1.The Role of Unfolded Protein Response in Cataract Pathogenesis;未折叠蛋白反应在白内障发病机制中作用的实验研究
2.The Study on Cholesterol Induced Unfolded Protein Response and ACAT2 Expression;胆固醇诱导的未折叠蛋白反应及其调节acat2基因表达的探讨
3.The Expression and Significance of the Correlation Factor of Unfolded Protein Response: XBP1、Bip and VEGF-C in Hepatocarcinoma;未折叠蛋白反应相关因子XBP1、Bip、VEGF-C在肝癌中的表达和意义的研究
4.Experimental Study on Effects of Targeted Agents on Unfolded Protein Response in Multiple Myeloma Cells;靶向治疗药物对骨髓瘤细胞未折叠蛋白反应影响的实验研究
5.Unfolded protein response involves in acute renal ischemia/reperfusion injury in mice未折叠蛋白反应参与小鼠急性肾缺血/再灌注损伤
6.Regulation of Cholesterol Transport-related Proteins Expressions by Oleic Acid-induced Endoplasmic Reticulum Stress in CaCo-2 Cells油酸通过未折叠蛋白反应调节肠粘膜上皮细胞胆固醇转运相关蛋白的表达
7.Electron microscopic localization of IRE1 on the retinal ganglion cells and oligodendrocytes on retinal nerve of the rat after optic nerve crushing视神经损伤后发生非折叠蛋白反应的超微证据
8.Unfolded Protein Response and Endoplasmic Reticulum Stress in Hereditary Inclusion Body Myopathy;遗传性包涵体肌病非折叠蛋白反应及内质网应激蛋白表达分析
9.chaperone protein伴侣蛋白质[可与新生、未折叠、错折叠或聚合的多肽相结合]
10.Unfolded Protein Responses of the Retinal Ganglion Cells after Optical Nerve Crash in Rats;大鼠视神经夹伤后视网膜节细胞的非折叠蛋白反应
11.A Research on Evidences on the Development of Unfolded Protein Responses in Optical Nerve after Its Injury视神经损伤后视神经发生非折叠蛋白反应的超微证据研究
12.Inhibition of Proteasome to Disrupt Unfolded Protein Response and Autophagy in Multiple Myeloma Cells抑制蛋白酶体干扰骨髓瘤细胞未折迭蛋白反应与自噬
13.Cholesterol Overloading Leads to Hepatic L02 Cell Damage Through Activation of the Unfolded Protein Response肝细胞高胆固醇负荷活化未折叠蛋白应答介导细胞凋亡损伤的研究
14.Protesome Inhibitors Induce Unfolded Protein Response and Apoptosis in Multiple Myeloma Cells;硼替佐米诱导骨髓瘤细胞未折迭蛋白反应及凋亡
15.Protein Pucker Simulation Based on Grid Computation Environment基于网格计算环境的蛋白质折叠模拟应用
16.A Novel Ensemble Classifier and Its Application in Protein Fold Recognition;一种高效集成分类器及其在蛋白质折叠识别中的应用研究
17.The Application of Distributed Parallel Processing and Complex Network in Protein Folding;分布式并行处理与复杂网络在蛋白质折叠中的应用
18.This becomes our prediction for the fold of that protein.这也就是我们对该蛋白质折叠的预测。
相关短句/例句
UPR未折叠蛋白反应
1.Objective:To study the role ofUPR in human cholangiocarcinoma cell(QBC939)and provide a new idea to cure cholangiocarcinoma.目的:研究UPR(未折叠蛋白反应,unfolded protein response)在QBc939细胞中的作用,为临床治疗胆管癌提供新思路。
2.In the last few years, researchers have shown how another cancer cell survival mechanism—the unfolded protein response, orUPR.目的研究UPR(未折叠蛋白反应,unfolded protein response)在QBC939细胞中的作用,为临床治疗胆管癌提供新思路。
pared with micelles alone,OA increased the spliced XBP1 mRNA levels and the protein expression of BIP and mature ATF6 in a concentration-dependent manner,leading to an induction of endoplasmic reticulum(ER) stress and activation of unfolded protein response(UPR).结论在有或无外源胆固醇的条件下,油酸通过未折叠蛋白反应差异地调节肠粘膜上皮细胞胆固醇转运相关蛋白的表达。
3)unfolded protein response未折叠蛋白质反应
1.Results cDNA microarray analysis demonstrated that there existsunfolded protein response in AsGnT-V7721 ce.方法用WesternBlot验证GnTⅤ的反义cDNA稳转的细胞株AsGnTⅤ7721(AsGnTⅤSMMC7721)中GnTⅤ表达,用基因芯片技术比较AsGnTⅤ7721与7721(SMMC7721)细胞的基因表达差异,同时用RTPCR和WesternBlot检测AsGnTⅤ7721细胞中未折叠蛋白质反应信号通路关键分子Bip和XBP1的表达变化。
4)endoplasmic reticulum unfolded protein response内质网未折叠蛋白反应
5)Unfolded protein response未折叠蛋白应答
1.The accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen causes ER stress response, activates the unfolded protein response (UPR) signal pathway and consequently induces the expression of ER-located molecular chaperones (such as BiP, calnexin, etc.真核细胞内质网中未折叠蛋白的积累会引起内质网胁迫(ER stress),激活未折叠蛋白应答(UPR)信号途径,从而诱导内质网中分子伴侣的表达(比如BiP和Calnexin等)。
2.To explore the possible mechanisms of cell damage resulted from cholesterol overloading in hepatocyte, the cell apoptosis, the unfolded protein response (UPR) and the correlation between them were tested in cholesterol-overloading human normal hepatic cell line L02.资料显示肝细胞胆固醇聚积可导致细胞损伤，为了探讨胆固醇负荷时肝细胞损伤作用及可能机制，我们体外检测了在胆固醇负荷条件下肝细胞的凋亡发生，未折叠蛋白应答活化，以及它们间的相关性。
6)unfolded protein response未折迭蛋白反应
1.To alleviate ER stress, MM cells activate a signaling pathway called theunfolded protein response (UPR), which aims to reestablish homeostasis by transmitting information to the nucleus about the protein-folding status in the ER lumen, triggering adaptive responses.ERS的生化基础称为未折迭蛋白反应(unfolded protein response,URP)。
延伸阅读
普通免疫球蛋白 ,人血丙种球蛋白,丙种球蛋白药物名称：丙种球蛋白英文名：γ-Globulin别名： 免疫血清球蛋白;普通免疫球蛋白 ,人血丙种球蛋白,丙种球蛋白外文名：γ－Globulin 适应症： 含有健康人群血清所具有的各种抗体，因而有增强机体抵抗力以预防感染的作用。主要用于免疫缺陷病以及传染性肝炎、麻疹、水痘、腮腺炎、带状皰疹等病毒感染和细菌感染的防治，也可用于哮喘、过敏性鼻炎、湿疹等内源性过敏性疾病。 用量用法： 肌注：每次２～５ｍｌ，３周１次，用于内源性过敏性疾病，每次１０ｍｌ（含量１０％者），３周内注射２次。胎盘球蛋白每次６～９ｍｌ。 注意事项： 1.按球蛋白来源可分为两种，一为健康人静脉血来源的丙种球蛋白制剂，按蛋白质含量有１０％、１６％、１６．５％等数种（国内制品浓度在１０％以上），其中丙种球蛋白占９５％以上。另一种为胎盘血来源的丙种球蛋白（人胎盘血丙种球蛋白），即胎盘球蛋白，含蛋白质５％，其中丙种球蛋白占９０％以上。胎盘球蛋白因丙种球蛋白含量以及纯度均较低，其用量应相应增大。 2.除专供静注用的制剂外，一般制剂不可静注。 3.注射大量时，可见局部疼痛和暂时性体温升高。 注：参见：“丙种球蛋白注射液”. 类别：免疫增强剂（免疫反应调节剂）
